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Hello @philipedwards
The one-click option in BWU dashboard will start the database backup and download it immediately, in case it got aborted during the process like this you will see the ERR_INVALID_RESPONSE, and this is caused by the server.. You can contact the hoster and tell them to increase the PHP max execution time so that one-click backup can work.
Or as a workaround, you can just create a new job which only backup database and run from there ^^
I hope my answer could help!