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Hi,
Thank you for reaching out.
Yes, BackWPUp is compatible with Multisite subdirectory mode. You can install the plugin on a multisite network and perform backups as usual. When it comes to restoring, you can simply restore the entire site at once since the backup includes both your database and files.
Regarding compatibility with xCloud LiteSpeed servers, there are no known major issues. However, we recommend testing the plugin in your specific environment to ensure everything operates smoothly.
If you encounter any issues or need further assistance, please feel free to contact us.
Thanks for your time.
Best regards,