This is certainly possible, without any code, using our Premium Templates. This extension includes a customizer that allows you to tailor your PDF documents, with product columns, totals rows, and custom blocks.
The customizer includes Product description columns for both short and long product description:
You can also use the placeholders {{product_description_short}},{{product_description_long}} or {{product_description_variation}} within Product column:
That said, if you have some PHP skills, we have an article in the plugin’s Docs about this subject, with some code snippets as examples: Displaying product description